Dimethyl-2,6-naphthalenedicarboxylate → Dimethyl 1,2,3,4-tetrahydronaphthalene-2,6-dicarboxylate
反応式
[CH:1]1[C:10]2[C:5](=[CH:6][C:7]([C:11]([O:13][CH3:14])=[O:12])=[CH:8][CH:9]=2)[CH:4]=[CH:3][C:2]=1[C:15]([O:17][CH3:18])=[O:16]>CC(O)=O.[Pd]>[CH2:6]1[C:5]2[C:10](=[CH:1][C:2]([C:15]([O:17][CH3:18])=[O:16])=[CH:3][CH:4]=2)[CH2:9][CH2:8][CH:7]1[C:11]([O:13][CH3:14])=[O:12]参加物
4
反応条件
- 温度
- 80 °C
実験手順
A mixture of dimethyl naphthalene-2,6-dicarboxylate (25.0 g, 102 mmol) and 5% Pd—C (5.0 g) in AcOH (75 mL) was shaken under an atmosphere of hydrogen (ca. 150 p.s.i.) at 80° C. for 6 h. The reaction mixture was cooled, purged with argon, and filtered through a pad of Celite, washing with AcOH. The filtrate was concentrated under reduced pressure to give the title compound. MS: m/z=249 (M+1).