Acetic Acid → Methyl 4-(2-acetylhydrazino)benzoate

HRID 133174

反応式

HRID 133174 の反応式
[NH:1]([C:3]1[CH:12]=[CH:11][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:5][CH:4]=1)[NH2:2].[CH3:13][C:14](O)=[O:15]>C([O-])(=O)C.[Na+]>[C:14]([NH:2][NH:1][C:3]1[CH:4]=[CH:5][C:6]([C:7]([O:9][CH3:10])=[O:8])=[CH:11][CH:12]=1)(=[O:15])[CH3:13]

参加物

4

反応物 2

HCID 176Acetic AcidHCID 408928Methyl 4-hydrazinylbenzoate

生成物 1

HCID 12765612Methyl 4-(2-acetylhydrazino)benzoate収率 115.7%

試薬・触媒・溶媒 1

HCID 517045Sodium Acetate溶媒

反応条件

温度
80 °C

実験手順

5.5 g of methyl 4-hydrazinobenzoate are dissolved in 38.2 ml of AcOH comprising 2.4 g of sodium acetate and the mixture is heated at 80° C. for 18 hours. The inorganic material is filtered off, the filtrate is then evaporated and the residue is taken up in the minimum amount of Et2O. The mixture is filtered to produce 7.97 g of the expected compound.

後処理

  1. filtrationThe inorganic material is filtered off
  2. customthe filtrate is then evaporated
  3. filtrationThe mixture is filtered

出典と根拠

ORDレコード
ord-07f58774b4744ce2b08cb56ac6cf1c96
出典データセット
uspto-grants-2008_06
特許番号
US07390818B2

関連ノート

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