2-Propenoic acid, 2-methyl-3-phenyl- → alpha-Methylhydrocinnamic acid
反応式
[CH3:1][C:2](=[CH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:3]([OH:5])=[O:4]>CO.[Pd]>[CH3:1][CH:2]([CH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)[C:3]([OH:5])=[O:4]参加物
4
実験手順
A solution of α-methyl cinnamic acid (10.0 g., 61.7 mmol.) in dry methanol (250 ml.) was treated with 10% palladium on carbon and hydrogenated (balloon used) at room temperature for 16 hours. The reaction mixture was diluted with methanol (250 ml.), filtered through a Celite pad in a millipore unit, washing the pad well with methanol (2×100 ml.). The clear filtrate was evaporated to dryness to give 10.225 g. of title product as a thick syrup.
後処理
- filtrationfiltered through a Celite pad in a millipore unit
- washwashing the pad well with methanol (2×100 ml.)
- customThe clear filtrate was evaporated to dryness
- customto give 10.225 g
出典と根拠
- ORDレコード
- ord-bc6e6e4b092043918a2288ce8fa820b4
- 出典データセット
- uspto-grants-1998_03
- 特許番号
- US05723602
反応ノート
読み込み中…