Dimethyl Sulfoxide → 11-{(S)-3-[2-(3-Fluoro-phenyl)-ethyl]-piperazin-1-yl}-3-methyl-5H-dibenzo[b,e][1,4]diazepine

反応式

Cl.[CH3:2][C:3]1[CH:4]=[C:5](N)[C:6]2[CH:12]=[N:11][C:10]3[CH:13]=[CH:14][CH:15]=[CH:16][C:9]=3[NH:8][C:7]=2[CH:17]=1.[F:19][C:20]1[CH:21]=[C:22]([CH2:26][CH2:27][C@H:28]2[CH2:33][NH:32][CH2:31][CH2:30][NH:29]2)[CH:23]=[CH:24][CH:25]=1.C(N(CC)C(C)C)(C)C.CS(C)=O>C(OCC)(=O)C.C1(C)C=CC=CC=1>[F:19][C:20]1[CH:21]=[C:22]([CH2:26][CH2:27][C@@H:28]2[NH:29][CH2:30][CH2:31][N:32]([C:12]3[C:6]4[CH:5]=[CH:4][C:3]([CH3:2])=[CH:17][C:7]=4[NH:8][C:9]4[CH:16]=[CH:15][CH:14]=[CH:13][C:10]=4[N:11]=3)[CH2:33]2)[CH:23]=[CH:24][CH:25]=1