1,2-Ethanediamine, N1-phenyl- → 2-Amino-4-(4,5-dihydro-furan-2-yl)-6-(2-phenylamino-ethylamino)-pyrimidine-5-carbonitrile

反応式

[NH2:1][C:2]1[N:7]=[C:6](OS(C(F)(F)F)(=O)=O)[C:5]([C:16]#[N:17])=[C:4]([C:18]2[O:19][CH2:20][CH2:21][CH:22]=2)[N:3]=1.[C:23]1([NH:29][CH2:30][CH2:31][NH2:32])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>COCCOC>[NH2:1][C:2]1[N:3]=[C:4]([C:18]2[O:19][CH2:20][CH2:21][CH:22]=2)[C:5]([C:16]#[N:17])=[C:6]([NH:32][CH2:31][CH2:30][NH:29][C:23]2[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=2)[N:7]=1

参加物

実験手順

From trifluoromethanesulfonic acid 2-amino-5-cyano-6-(4,5-dihydro-furan-2-yl)-pyrimidin-4-yl ester and N-phenylethylenediamine in DME. ES-MS m/e (%): 323 (M+H+, 100).

出典と根拠

ORDレコード: ord-3044f3acc88542069d19f21a1000a70a
出典データセット: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06586441B2

反応ノート

読み込み中…

参加物

反応物 2

HCID 742701,2-Ethanediamine, N1-phenyl-

HCID 86583757Trifluoromethanesulfonic acid 2-amino-5-cyano-6-(4,5-dihydro-furan-2-yl)-pyrimidin-4-yl ester

生成物 1

HCID 185074712-Amino-4-(4,5-dihydro-furan-2-yl)-6-(2-phenylamino-ethylamino)-pyrimidine-5-carbonitrile

試薬・触媒・溶媒 1

HCID 80711,2-Dimethoxyethane溶媒

実験手順

From trifluoromethanesulfonic acid 2-amino-5-cyano-6-(4,5-dihydro-furan-2-yl)-pyrimidin-4-yl ester and N-phenylethylenediamine in DME. ES-MS m/e (%): 323 (M+H+, 100).

出典と根拠

ORDレコード: ord-3044f3acc88542069d19f21a1000a70a
出典データセット: uspto-grants-2003_07
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06586441B2

反応ノート

読み込み中…