Tributylstannane → Bis[1-(3-hydroxypropoxy)-2,2,6,6-tetramethylpiperidin-4-yl]Sebacate

HRID 1356919ノート

反応式

HRID 1356919 の反応式
C([SnH](C[CH2:11][CH2:12][CH3:13])CCCC)CCC.Br[CH2:15][CH2:16][CH2:17][OH:18].[OH:19][N:20]1[C:25]([CH3:27])([CH3:26])[CH2:24][CH:23]([O:28][C:29](=[O:52])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][C:38]([O:40][CH:41]2[CH2:46][C:45]([CH3:48])([CH3:47])[N:44]([OH:49])[C:43]([CH3:51])([CH3:50])[CH2:42]2)=[O:39])[CH2:22][C:21]1([CH3:54])[CH3:53].CCCCCCC.CCCCCCC.C(OCC)(=[O:71])C>ClC1C=CC=CC=1>[OH:18][CH2:17][CH2:16][CH2:15][O:49][N:44]1[C:43]([CH3:51])([CH3:50])[CH2:42][CH:41]([O:40][C:38](=[O:39])[CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][C:29]([O:28][CH:23]2[CH2:24][C:25]([CH3:27])([CH3:26])[N:20]([O:19][CH2:13][CH2:12][CH2:11][OH:71])[C:21]([CH3:54])([CH3:53])[CH2:22]2)=[O:52])[CH2:46][C:45]1([CH3:48])[CH3:47]

参加物

7

反応物 5

HCID 5948TributylstannaneHCID 8900HeptaneHCID 123083-Bromo-1-propanolHCID 11272241Bis(1-hydroxy-2,2,6,6-tetramethyl-4-piperidinyl)decandioateHCID 21899848Ethylacetate heptane

生成物 1

HCID 22507641Bis[1-(3-hydroxypropoxy)-2,2,6,6-tetramethylpiperidin-4-yl]Sebacate

試薬・触媒・溶媒 1

HCID 7964Chlorobenzene溶媒

実験手順

Tributyltin hydride is added dropwise to a solution of 3-bromo-1-propanol and excess bis(1-oxyl-2,2,6,6-tetramethylpiperidin-4-yl)sebacate in chlorobenzene. The mixture is heated to facilitate reaction. The crude reaction mixture is passed through silica gel with heptane and then heptane/ethyl acetate to afford the title compound.

後処理

  1. temperatureThe mixture is heated
  2. customreaction
  3. customThe crude reaction mixture

出典と根拠

ORDレコード
ord-99aa69721d1c434d808f27a7b5fa2666
出典データセット
uspto-grants-2003_07
特許番号
US06586507B2

反応ノート

読み込み中…