Thionyl Chloride → 2-(chloromethyl)-1,3-dimethoxyBenzene

HRID 1357032

反応式

HRID 1357032 の反応式
[CH3:1][O:2][C:3]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][CH3:12])[C:4]=1[CH2:5]O.S(Cl)([Cl:15])=O>C1C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][CH3:12])[C:4]=1[CH2:5][Cl:15]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 2776839(2,6-Dimethoxyphenyl)methanol

生成物 1

HCID 127070022-(chloromethyl)-1,3-dimethoxyBenzene

試薬・触媒・溶媒 1

HCID 241Benzene溶媒

実験手順

1.86 g (11.1 mmol) of 2,6-dimethoxybenzyl alcohol was dissolved in 15 ml of benzene, and the resultant solution was cooled to 5° C. The solution was then added with 1.55 g (13.0mmol) of thionyl chloride at the same temperature. The mixture was subjected to temperature elevation up to a room temperature, then stirred for 70 min. to complete a reaction. The reacted solution was condensed under reduced pressure to thereby obtain a crude product of 2,6-dimethoxybenzyl chloride.

後処理

  1. customwas subjected to temperature elevation up to a room temperature
  2. customa reaction
  3. customcondensed under reduced pressure

出典と根拠

ORDレコード
ord-58268e70e27d436d9cb3348c60b05ae3
出典データセット
uspto-grants-2003_07
特許番号
US06589967B1

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