Water → 4-Azidobenzaldehyde
反応式
F[C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1.[N-:10]=[N+:11]=[N-:12].[Na+].O>CS(C)=O>[N:10]([C:2]1[CH:9]=[CH:8][C:5]([CH:6]=[O:7])=[CH:4][CH:3]=1)=[N+:11]=[N-:12]参加物
5
反応条件
- 温度
- 105 °C
実験手順
50 g 4-fluoro benzaldehyde and 50 g sodium azide were dispersed in 150 ml dry dimethyl sulfoxide. Subsequently, the mixture was heated for 3 hours at 105° C. while nitrogen was introduced. The mixture was poured into 200 ml water, and the solution extracted with 200 ml dichloro methane (three times). Then the solvent was distilled off by means of a vacuum rotation vaporizer. 53 g of a liquid remained having infrared (IR) and nuclear magnetic resonance (NMR) spectra consistent with the 4-azido benzaldehyde structure.
後処理
- additionwas introduced
- extractionthe solution extracted with 200 ml dichloro methane (three times)
- distillationThen the solvent was distilled off by means of a vacuum rotation vaporizer
出典と根拠
- ORDレコード
- ord-83d9711f65f642a6b84fcbd04a7e823b
- 出典データセット
- uspto-grants-2003_07
- 特許番号
- US06596460B2
反応ノート
読み込み中…