Potassium Carbonate → HCID 178515855、化合物
反応式
[CH2:1]([C:8]1[C:13]([Br:14])=[CH:12][N:11]=[C:10]([O:15]C)[CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+]>Br>[CH2:1]([C:8]1[C:13]([Br:14])=[CH:12][N:11]=[C:10]([OH:15])[CH:9]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1参加物
4
実験手順
250 ml of 47% hydrobromic acid was added to 62 g of 4-benzyl-5-bromo-2-methoxypyridine, followed by heating under stirring for 3 hours in an oil bath kept at 100° C. After cooling as it was, the reaction solution was added to an aqueous potassium carbonate solution little by little and neutralized. The resulting precipitates were collected by filtration, to give 59 g of the target compound.
後処理
- temperatureby heating
- customkept at 100° C
- temperatureAfter cooling as it
- customThe resulting precipitates
- filtrationwere collected by filtration
出典と根拠
- ORDレコード
- ord-8c821cdfdc234599beec1c2f718899b5
- 出典データセット
- uspto-grants-2003_07
- 特許番号
- US06599917B1
反応ノート
読み込み中…