Thionyl Chloride → HCID 22145275、化合物
反応式
[CH2:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][CH2:10][C:11]([OH:13])=O)[CH3:2].S(Cl)([Cl:16])=O>C1(C)C=CC=CC=1>[CH2:1]([C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH2:9][CH2:10][C:11]([Cl:16])=[O:13])[CH3:2]参加物
4
実験手順
A mixture of 3-(2-ethylphenyl)propanoic acid (prepared in 3 steps from 1-ethyl-2-iodobenzene, 4.24 g, 23.8 mmole), thionyl chloride (9.50 ml, 130 mmol) and toluene (100 ml) was refluxed for 2 hours. Concentration in vacuo gave 3-(2-ethylphenyl)propanoyl chloride which was taken up in methylene chloride and used in the next step as a crude.
後処理
- temperaturewas refluxed for 2 hours
- concentrationConcentration in vacuo
出典と根拠
- ORDレコード
- ord-5c1cb8e628a940c689106472e574419d
- 出典データセット
- uspto-grants-2003_07
- 特許番号
- US06600015B2
反応ノート
読み込み中…