Butyl iodide → a-3-Butoxy-4-iodobenzaldehyde
反応式
I[CH2:2][CH2:3][CH2:4][CH3:5].O[C:7]1[CH:8]=[C:9]([CH:12]=[CH:13][C:14]=1[I:15])[CH:10]=[O:11].C(=O)([O-])[O-:17].[K+].[K+]>C(C(C)=O)C>[CH3:2][CH2:3][CH:4]([O:11][C:10](=[O:17])[C:9]1[CH:12]=[CH:13][C:14]([I:15])=[CH:7][CH:8]=1)[CH3:5]参加物
5
反応条件
- 温度
- 85 °C
実験手順
21.5 ml (189 mmol) of 1-iodobutane are added to a solution of 31 g (126 mmol) of 3-hydroxy-4-iodobenzaldehyde in 350 ml of methyl ethyl ketone in the presence of 52.2 g (378 mmol) of potassium carbonate. The reaction medium is heated at 85° C. for 2 hours. The solid is filtered off and the solvent is evaporated off. The solid obtained is washed with heptane and 38 g (99%) of 3-butoxy-4-iodobenzaldehyde are obtained in the form of white crystals.
後処理
- filtrationThe solid is filtered off
- customthe solvent is evaporated off
- customThe solid obtained
- washis washed with heptane and 38 g (99%) of 3-butoxy-4-iodobenzaldehyde
- customare obtained in the form of white crystals
出典と根拠
- ORDレコード
- ord-19ec1e0758054348959839dc5e37f8e8
- 出典データセット
- uspto-grants-2011_02
- 特許番号
- US07879907B2
反応ノート
読み込み中…