Water → [4-(2-Methylpropyl)phenyl]methanol
反応式
[CH2:1]([C:5]1[CH:12]=[CH:11][C:8]([CH:9]=[O:10])=[CH:7][CH:6]=1)[CH:2]([CH3:4])[CH3:3].[BH4-].[Na+].O>CO>[CH2:1]([C:5]1[CH:6]=[CH:7][C:8]([CH2:9][OH:10])=[CH:11][CH:12]=1)[CH:2]([CH3:4])[CH3:3]参加物
5
実験手順
To a solution of 4-isobutylbenzaldehyde (2.4 g) in methanol (10 mL) was added sodium borohydride (0.85 g) at room temperature, and the mixture was stirred at room temperature overnight. Water was added to the reaction mixture, and the mixture was extracted with diethyl ether. The organic layer was washed with water and brine, and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure to give the title compound (2.3 g).
後処理
- extractionthe mixture was extracted with diethyl ether
- washThe organic layer was washed with water and brine
- dry with materialdried over anhydrous magnesium sulfate
- customThe solvent was removed under reduced pressure
出典と根拠
- ORDレコード
- ord-25c886ccb1fc4f2cbe5baa6204761d0a
- 出典データセット
- uspto-grants-2011_02
- 特許番号
- US07888487B2
反応ノート
読み込み中…