Thionyl Chloride → Methyl 3-chlorocarbonyl-2,4-dichlorobenzoate
反応式
S(Cl)([Cl:3])=O.[Cl:5][C:6]1[C:15]([C:16](O)=[O:17])=[C:14]([Cl:19])[CH:13]=[CH:12][C:7]=1[C:8]([O:10][CH3:11])=[O:9]>CN(C)C=O.C1(C)C=CC=CC=1>[Cl:3][C:16]([C:15]1[C:6]([Cl:5])=[C:7]([CH:12]=[CH:13][C:14]=1[Cl:19])[C:8]([O:10][CH3:11])=[O:9])=[O:17]参加物
5
実験手順
2 drops of dimethylformamide and 11.90 g (0.1 mol) of thionyl chloride were added to a solution of 5.00 g (0.02 mol) of methyl 2,4-dichloro-3-hydroxycarbonylbenzoate and 50 ml of dry toluene. The solution was heated under reflux for 4 hours. Removal of the solvent by distillation gave 5.35 g of methyl 3-chlorocarbonyl-2,4-dichlorobenzoate.
後処理
- temperatureThe solution was heated
- temperatureunder reflux for 4 hours
- customRemoval of the solvent
- distillationby distillation
出典と根拠
- ORDレコード
- ord-5f793e16d369460e90d5794f30d8cbc0
- 出典データセット
- uspto-grants-2003_06
- 特許番号
- US06576596B1
反応ノート
読み込み中…