Oxalyl chloride → HCID 22609552、化合物

HRID 1368924ノート

反応式

HRID 1368924 の反応式
[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:13]=[CH:14]/[CH:15]=[CH:16]/[C:17]([OH:19])=O)[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10].C(Cl)(=O)C([Cl:23])=O>CN(C)C=O.C(Cl)Cl>[CH3:1][O:2][C:3]1[CH:4]=[C:5](/[CH:13]=[CH:14]/[CH:15]=[CH:16]/[C:17]([Cl:23])=[O:19])[CH:6]=[C:7]([O:11][CH3:12])[C:8]=1[O:9][CH3:10]

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 15257506HCID 15257506、化合物

生成物 1

HCID 22609552HCID 22609552、化合物

試薬・触媒・溶媒 1

HCID 22350042dichloromethane N,N-dimethylformamide溶媒

実験手順

A solution of 174 mg (0.66 mmol) of 5-(3,4,5-trimethoxyphenyl)penta-(2E,4E)-dienoic acid in anhydrous dimethylformamide-methylene chloride (0.1 ml-5 ml) was cooled in an ice bath, and to the solution was added 0.080 ml (0.92 mmol) of oxalyl chloride with stirring. The ice bath was removed, and the mixture was stirred for 30 minutes at room temperature. The reaction mixture was concentrated under reduced pressure to obtain crude crystals of 5-(3,4,5-trimethoxyphenyl)penta-(2E, 4E)-dienoyl chloride.

後処理

  1. customThe ice bath was removed
  2. stirringthe mixture was stirred for 30 minutes at room temperature
  3. concentrationThe reaction mixture was concentrated under reduced pressure

出典と根拠

ORDレコード
ord-b672e62a73384d0c8a65c792103c6490
出典データセット
uspto-grants-2003_06
特許番号
US06576642B2

反応ノート

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