Methanone, (4-nitrophenyl)phenyl- → 4-Aminobenzophenone

HRID 1368947ノート

反応式

HRID 1368947 の反応式
[N+:1]([C:4]1[CH:17]=[CH:16][C:7]([C:8]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[O:9])=[CH:6][CH:5]=1)([O-])=O>C(O)C.ClCCl.[Pd]>[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([C:8]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)=[O:9])=[CH:16][CH:17]=1

参加物

4

反応物 1

HCID 70839Methanone, (4-nitrophenyl)phenyl-

生成物 1

HCID 143464-Aminobenzophenone

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 21584144Dichloromethane ethanol溶媒

実験手順

4-Nitrobenzophenone (5.0 g, 0.022 mol) is dissolved in ethanol-dichloromethane (40 ml:30 ml) and hydrogenated at room temperature with 10% palladium on carbon (0.5 g) as a catalyst. The catalyst is filtered off and the filtrate is evaporated to dryness. The product is used in the next reaction step without further purification. Yield 5.2 g.

後処理

  1. filtrationThe catalyst is filtered off
  2. customthe filtrate is evaporated to dryness
  3. customThe product is used in the next reaction step without further purification

出典と根拠

ORDレコード
ord-6739355601ed42fb8d669827d530fd96
出典データセット
uspto-grants-2003_06
特許番号
US06576645B1

反応ノート

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