Thioacetamide → 3,4-Diethoxybenzene-1-carbothioamide
反応式
[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1[O:12][CH2:13][CH3:14])[C:7]#[N:8])[CH3:2].C(N)(=[S:17])C>Cl.CN(C=O)C>[CH2:1]([O:3][C:4]1[CH:5]=[C:6]([CH:9]=[CH:10][C:11]=1[O:12][CH2:13][CH3:14])[C:7]([NH2:8])=[S:17])[CH3:2]参加物
4
実験手順
A solution of 29 g of 3,4-diethoxybenzonitrile and 23 g of thioacetamide in 120 ml of 10% hydrochloric acid-DMF was stirred at 90° C. for 3 hours and then 130° C. for 5 hours. After evaporation of the solvent, the residue was washed with diethyl ether (2×100 ml) and water (2×100 ml). The resulting crystals were collected by filtration and dried to obtain 21.7 g of 3,4-diethoxythiobenzamide.
後処理
- customAfter evaporation of the solvent
- washthe residue was washed with diethyl ether (2×100 ml) and water (2×100 ml)
- filtrationThe resulting crystals were collected by filtration
- customdried
出典と根拠
- ORDレコード
- ord-ddc63047cca2436481bdc6795ef376f5
- 出典データセット
- uspto-grants-2003_06
- 特許番号
- US06583163B2
反応ノート
読み込み中…