Hydrochloric Acid → HCID 22607995、化合物
反応式
[C:1]1([S:7][C:8]2[CH:9]=[C:10]([CH:14]3OCC[O:15]3)[CH:11]=[CH:12][CH:13]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl>C(#N)C>[C:1]1([S:7][C:8]2[CH:9]=[C:10]([CH:11]=[CH:12][CH:13]=2)[CH:14]=[O:15])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1参加物
4
実験手順
Combine 2-(3-phenylsulfanylphenyl)-[1,3]-dioxolane (0.3 g, 1.1 mmol) and acetonitrile (8.0 ml) add a solution of hydrochloric acid (1N, 2.0 ml). After 18 hours, concentrate in vacuum to remove most of the acetonitrile, dilute with water and extract with ether. Combine the organic extracts and wash once with saturated sodium bicarbonate, then with brine. Dry (Na2SO4) the organics, filter, and concentrated to give the title compound.
後処理
- concentrationconcentrate in vacuum
- customto remove most of the acetonitrile
- additiondilute with water
- extractionextract with ether
- washwash once with saturated sodium bicarbonate
- dry with materialDry (Na2SO4) the organics,
- filtrationfilter
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-3a81f9daeeb04bad8c589b50f3f5a9b8
- 出典データセット
- uspto-grants-2007_01
- 特許番号
- US07157488B2
反応ノート
読み込み中…