化工社化工社 化学情報印刷レポート · 研究参考用
2-Dimethylaminopyridine → HCID 178469736、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Dimethylaminopyridine | HCID 21885 | — |
| 反応物 | Ethyl 4-chloro-2-phenylpyrimidine-5-carboxylate | HCID 239537 | — |
| 反応物 | HCID 178419079 | HCID 178419079 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | HCID 178469736 | HCID 178469736 | — |
反応手順
Ethyl 4-chloro-2-phenyl-5-pyrimidinecarboxylate and N-tert-butoxycarbonyl-trans-1,4-cyclohexanediamine were reacted in ethanol in the presence of dimethylaminopyridine in the same manner as in Reference Example 3-49 to obtain N-tert-butoxycarbonyl-trans-4-(5-ethoxycarbonyl-2-phenyl-4-pyrimidinylamino)cyclohexylamine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07160877B2 |
| 出典データセット | uspto-grants-2007_01 |
| ORD ID | ord-7cdd0e493b5a4360ae82acfd3eef692d |
| 出典メモ | uspto-grants-2007_01 |