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HRID1373027

反应详情

EQUATION

反应方程式

HRID 1373027 的结构方程式

REACTANTS

反应物

3
结构：CN(C)c1ccccn1
HCID21885

2-Dimethylaminopyridine

C7H10N2

结构：CCOC(=O)c1cnc(-c2ccccc2)nc1Cl
HCID239537

ethyl 4-chloro-2-phenylpyrimidine-5-carboxylate

C13H11ClN2O2

结构：CC(C)(C)OC(=O)N[C@H]1CC[C@H](N)CC1
HCID178419079

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)c1cnc(-c2ccccc2)nc1N[C@H]1CC[C@H](NC(=O)OC(C)(C)C)CC1
HCID178469736

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCO
溶剂HCID702

Ethanol

C2H6O

PROCEDURE

实验过程

Ethyl 4-chloro-2-phenyl-5-pyrimidinecarboxylate and N-tert-butoxycarbonyl-trans-1,4-cyclohexanediamine were reacted in ethanol in the presence of dimethylaminopyridine in the same manner as in Reference Example 3-49 to obtain N-tert-butoxycarbonyl-trans-4-(5-ethoxycarbonyl-2-phenyl-4-pyrimidinylamino)cyclohexylamine.