Nitrobenzene → 1-(4-Nitrophenyl)-4-imidazolidinone

HRID 1373165ノート

反応式

HRID 1373165 の反応式
[NH:1]1[CH2:5][C:4](=[O:6])[NH:3][CH2:2]1.[N+:7]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)([O-:9])=[O:8].C(N(C(C)C)CC)(C)C>CN(C=O)C>[N+:7]([C:10]1[CH:15]=[CH:14][C:13]([N:1]2[CH2:5][C:4](=[O:6])[NH:3][CH2:2]2)=[CH:12][CH:11]=1)([O-:9])=[O:8]

参加物

5

反応物 3

HCID 7416NitrobenzeneHCID 81531DiisopropylethylamineHCID 15020634-Imidazolidinone

生成物 1

HCID 210742741-(4-Nitrophenyl)-4-imidazolidinone

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

A solution of 4-imidazolidinone (9.5 g, 110.5 mmol), 4-nitrobenzene (1 eq) and diisopropyl ethylamine (28.6 mL, 165 mmol) in dry DMF (80 mL) was heated to 60° C. overnight under argon. The reaction mixture was allowed to cool to room temperature and ice pieces were added. The solid formed was filtered and washed with water. The solid was air dried to yield the nitro compound as yellow crystals.

後処理

  1. additionice pieces were added
  2. customThe solid formed
  3. filtrationwas filtered
  4. washwashed with water
  5. customdried

出典と根拠

ORDレコード
ord-fbcb744e7e664f68805ac3377625e719
出典データセット
uspto-grants-2007_01
特許番号
US07160912B2

反応ノート

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