Triethylamine → methyl 2,4-dichloro-6-(5-fluoro-6-((R)-1-(1-(2,2,2-trifluoroacetamido)cyclopropanecarboxamido)ethyl)pyridin-3-yl)benzoate

反応式

[Cl-].[Cl:2][C:3]1[C:4]([C:20]([O:22][CH3:23])=[O:21])=[C:5]([C:10]2[CH:11]=[C:12]([F:19])[C:13]([C@H:16]([NH3+:18])[CH3:17])=[N:14][CH:15]=2)[CH:6]=[C:7]([Cl:9])[CH:8]=1.[F:24][C:25]([F:36])([F:35])[C:26]([NH:28][C:29]1([C:32](O)=[O:33])[CH2:31][CH2:30]1)=[O:27].Cl.C(N=C=NCCCN(C)C)C.ON1C2N=CC=CC=2N=N1.C(N(CC)CC)C>C(Cl)Cl>[Cl:2][C:3]1[CH:8]=[C:7]([Cl:9])[CH:6]=[C:5]([C:10]2[CH:15]=[N:14][C:13]([C@H:16]([NH:18][C:32]([C:29]3([NH:28][C:26](=[O:27])[C:25]([F:24])([F:35])[F:36])[CH2:30][CH2:31]3)=[O:33])[CH3:17])=[C:12]([F:19])[CH:11]=2)[C:4]=1[C:20]([O:22][CH3:23])=[O:21]