tert-butyl (4R)-4-{[(benzyloxy)carbonyl]amino}pentanoate → HCID 58781983、化合物
反応式
C(OC([NH:11][C@H:12]([CH3:22])[CH2:13][CH2:14][C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16])=O)C1C=CC=CC=1>CO.[Pd]>[NH2:11][C@H:12]([CH3:22])[CH2:13][CH2:14][C:15]([O:17][C:18]([CH3:21])([CH3:20])[CH3:19])=[O:16]参加物
4
実験手順
To a solution of tert-butyl (4R)-4-{[(benzyloxy)carbonyl]amino}pentanoate (3.5 g, 11.4 mmol) in methanol (35 ml) was added Pd—C (0.7 g) and the mixture was stirred under a hydrogen atomosphere for 3 hours. Catalyst was-removed by filtration and the solvent was removed in vacuo to give tert-butyl(4R)-4-aminopentanoate (2.1 g).
後処理
- customCatalyst was-removed by filtration
- customthe solvent was removed in vacuo
出典と根拠
- ORDレコード
- ord-62a1634cec9145a4826dd171d59b7ea3
- 出典データセット
- uspto-grants-2007_01
- 特許番号
- US07163936B2
反応ノート
読み込み中…