Water → HCID 21078429、化合物
反応式
[C:1]([C:3]1[CH:4]=[C:5]([O:9][CH:10]([CH2:15][CH3:16])[C:11]([O:13]C)=[O:12])[CH:6]=[N:7][CH:8]=1)#[N:2].[OH-].[Na+].O>CC(O)C>[C:1]([C:3]1[CH:4]=[C:5]([O:9][CH:10]([CH2:15][CH3:16])[C:11]([OH:13])=[O:12])[CH:6]=[N:7][CH:8]=1)#[N:2]参加物
5
実験手順
The product from Step 1 (0.29 g) was dissolved in propan-2-ol (5 ml) containing sodium hydroxide (0.053 g) and water (2 ml). The mixture was stirred at ambient temperature for 20 minutes, evaporated under reduced pressure to a small volume and diluted with water. The solution was acidified with dilute aqueous hydrochloric acid and extracted with ethyl acetate (three times). The extracts were combined, washed with water (three times), dried over magnesium sulphate and evaporated under reduced pressure to give the required product, 0.25 g, as a gum.
後処理
- customevaporated under reduced pressure to a small volume
- additiondiluted with water
- extractionextracted with ethyl acetate (three times)
- washwashed with water (three times)
- dry with materialdried over magnesium sulphate
- customevaporated under reduced pressure
出典と根拠
- ORDレコード
- ord-daa26ae21a3d4d0589df7f32e6aef40b
- 出典データセット
- uspto-grants-2007_01
- 特許番号
- US07166621B2
反応ノート
読み込み中…