5-(2-Butyl-1,3-dithiolan-2-yl)benzene-1,3-diol → 5-(2-Cyclohexyl-[1,3]dithiolan-2-yl)-benzene-1,3-diol

HRID 1376247

反応式

HRID 1376247 の反応式
[CH:1]1([C:7]2([C:12]3[CH:17]=[C:16]([O:18]C)[CH:15]=[C:14]([O:20]C)[CH:13]=3)[S:11][CH2:10][CH2:9][S:8]2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.C(C1(C2C=C(O)C=C(O)C=2)SCCS1)CCC>CCCCCC.C(OCC)(=O)C>[CH:1]1([C:7]2([C:12]3[CH:17]=[C:16]([OH:18])[CH:15]=[C:14]([OH:20])[CH:13]=3)[S:8][CH2:9][CH2:10][S:11]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

参加物

4

反応物 2

HCID 3176955-(2-Butyl-1,3-dithiolan-2-yl)benzene-1,3-diolHCID 858840912-Cyclohexyl-2-(3,5-dimethoxy-phenyl)-[1,3]dithiolane

生成物 1

HCID 858841005-(2-Cyclohexyl-[1,3]dithiolan-2-yl)-benzene-1,3-diol

試薬・触媒・溶媒 1

HCID 21226206Ethyl acetate hexane溶媒

実験手順

Compound 18 was prepared from Compound 11 using the same procedure as described above for Compound 16. Yield 0.853 g (62.2%) as a waxy solid. Rf=0.27 (hexane:ethyl acetate 8:2); 1H NMR δ 6.78 (d, J=0.9 Hz, 2H), 6.19 (t, J=1.95 Hz, 1H), 4.14 (br s, 2H), 3.32–3.07 (m, 4H), 2.15–2.06 (m, 1H), 1.96–1.58 (m, 4H), 1.19–1.00 (m, 4H); 13C NMR δ 156.95, 147.94, 107.39, 101.12, 80.58, 60.83, 50.56, 38.82, 30.92, 26.77, 26.24, 21.08, 14.17; MS: (ESI, Neg.) m/z 295 ([M−H]−).

出典と根拠

ORDレコード
ord-e72c13d807084fbf9fabfd0c3516afa4
出典データセット
uspto-grants-2007_01
特許番号
US07169942B2

関連ノート

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