5-Nitro-4,7-dimethyl-1,3-benzodioxole → 5-Amino-4,7-dimethyl-1,3-benzodioxole
反応式
[N+:1]([C:4]1[CH:12]=[C:11]([CH3:13])[C:7]2[O:8][CH2:9][O:10][C:6]=2[C:5]=1[CH3:14])([O-])=O.[H][H]>[Pd].C(O)C>[NH2:1][C:4]1[CH:12]=[C:11]([CH3:13])[C:7]2[O:8][CH2:9][O:10][C:6]=2[C:5]=1[CH3:14]参加物
5
実験手順
A mixture of 1.88 g of 5-nitro-4,7-dimethyl-1,3-benzodioxole and 0.19 g of 10% palladium on carbon in 200 mL of ethanol is placed under a 50 psi hydrogen atmosphere. The mixture is shaken for 90 minutes at room temperature. The reaction mixture is filtered through Celite to yield a brownish solution. Concentration under reduced pressure affords 1.59 g of 5-amino-4,7-dimethyl-1,3-benzodioxole.
後処理
- filtrationThe reaction mixture is filtered through Celite
- customto yield a brownish solution
- concentrationConcentration under reduced pressure
出典と根拠
- ORDレコード
- ord-bc99ec18769f4c8e9a650dd71a101f80
- 出典データセット
- uspto-grants-1997_09
- 特許番号
- US05663189
反応ノート
読み込み中…