化工社化工社 化学情報印刷レポート · 研究参考用
Thionyl Chloride → 5-Bromonicotinoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 5-Bromonicotinic acid | HCID 88707 | — |
| 生成物 | 5-Bromonicotinoyl chloride | HCID 2781223 | — |
反応手順
To 5.00 g of 5-bromonicotinic acid, 74 ml of thionyl chloride was added and the mixture was heated at reflux for 6 hours. After the solvent was distilled off under reduced pressure, the crystal was washed with diisopropyl ether and collected by filtration to obtain 4.09 g of the objective compound as colorless crystals.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07728131B2 |
| 出典データセット | uspto-grants-2010_06 |
| ORD ID | ord-13b18ee5ae764080a25434c0db579b45 |
| 出典メモ | uspto-grants-2010_06 |