Diisopropylethylamine → 4-[4-(2-fluoroethyl)piperazin-1-ylmethyl]-3-trifluoromethyl-N-{4-methyl-3-[4-(5-pyrimidinyl)pyrimidin-2-ylamino]phenyl}benzamide

反応式

[F:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][N:7]([CH2:10][C:11]2[CH:19]=[CH:18][C:14]([C:15](O)=[O:16])=[CH:13][C:12]=2[C:20]([F:23])([F:22])[F:21])[CH2:6][CH2:5]1.[I-].ClC1C=CC=C[N+]=1C.[CH3:33][C:34]1[CH:40]=[CH:39][C:37]([NH2:38])=[CH:36][C:35]=1[NH:41][C:42]1[N:47]=[C:46]([C:48]2[CH:49]=[N:50][CH:51]=[N:52][CH:53]=2)[CH:45]=[CH:44][N:43]=1.C(N(C(C)C)CC)(C)C>CN(C)C=O.O>[F:1][CH2:2][CH2:3][N:4]1[CH2:9][CH2:8][N:7]([CH2:10][C:11]2[CH:19]=[CH:18][C:14]([C:15]([NH:38][C:37]3[CH:39]=[CH:40][C:34]([CH3:33])=[C:35]([NH:41][C:42]4[N:47]=[C:46]([C:48]5[CH:53]=[N:52][CH:51]=[N:50][CH:49]=5)[CH:45]=[CH:44][N:43]=4)[CH:36]=3)=[O:16])=[CH:13][C:12]=2[C:20]([F:23])([F:21])[F:22])[CH2:6][CH2:5]1