Dichloromethane → HCID 23682646、化合物

HRID 1379799ノート

反応式

HRID 1379799 の反応式
[OH-].[Na+:2].[C:3]([C:5]1[CH:25]=[CH:24][C:8]([C:9]([N:11]=[C:12]2[N:16]([CH3:17])[C:15]([CH3:18])=[C:14]([C:19]([O:21]CC)=[O:20])[S:13]2)=[O:10])=[CH:7][CH:6]=1)#[N:4].C(Cl)Cl>CO>[C:3]([C:5]1[CH:25]=[CH:24][C:8]([C:9]([N:11]=[C:12]2[N:16]([CH3:17])[C:15]([CH3:18])=[C:14]([C:19]([O-:21])=[O:20])[S:13]2)=[O:10])=[CH:7][CH:6]=1)#[N:4].[Na+:2]

参加物

5

反応物 3

HCID 6344DichloromethaneHCID 14798Sodium HydroxideHCID 4249922HCID 4249922、化合物

生成物 1

HCID 23682646HCID 23682646、化合物

試薬・触媒・溶媒 1

HCID 887Methanol溶媒

実験手順

10% Aqueous sodium hydroxide solution (48 ml) was added to a mixture of ethyl 2-(4-cyanobenzoylimino)-3,4-dimethylthiazoline-5-carboxylate (9.88 g), methylene chloride (250 ml) and methanol (250 ml), followed by stirring at room temperature for 17 hours. The reaction mixture was concentrated under reduced pressure, and the precipitated crystals were collected by filtration to give sodium 2-(4-cyanobenzoylimino)-3,4-dimethylthiazoline-5-carboxylate (10.0 g).

後処理

  1. concentrationThe reaction mixture was concentrated under reduced pressure
  2. filtrationthe precipitated crystals were collected by filtration

出典と根拠

ORDレコード
ord-10a66edc96fc466d824e4ad2fd402eae
出典データセット
uspto-grants-1997_09
特許番号
US05672712

反応ノート

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