4(Fluoromethyl-ethyl)-nitrobenzene → 4(1-Fluoromethyl-ethyl)-aniline

HRID 1379973ノート

反応式

HRID 1379973 の反応式
[F:1][CH2:2][CH:3]([C:5]1[CH:10]=[CH:9][C:8]([N+:11]([O-])=O)=[CH:7][CH:6]=1)[CH3:4]>CO.[Pd]>[F:1][CH2:2][CH:3]([C:5]1[CH:10]=[CH:9][C:8]([NH2:11])=[CH:7][CH:6]=1)[CH3:4]

参加物

4

反応物 1

HCID 131873674(Fluoromethyl-ethyl)-nitrobenzene

生成物 1

HCID 131873684(1-Fluoromethyl-ethyl)-aniline

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

10.3 g (0.057 Mol) 4(1-fluoromethyl-ethyl)-nitrobenzene are dissolved in 250 ml absolute CH3OH and hydrogenated at room temperature and atmospheric pressure in the presence of 0.61 g 10% Pd/C.

出典と根拠

ORDレコード
ord-7ba063574cf745628233321543db1a15
出典データセット
uspto-grants-1986_04
特許番号
US04579585

反応ノート

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