Sodium Bicarbonate → HCID 178502658、化合物
反応式
[C:1]([CH2:6][N:7]1[C:11]([SH:12])=[N:10][N:9]=[N:8]1)([C:3]([OH:5])=[O:4])=O.Cl.[CH3:14][O:15][NH2:16].C(=O)(O)[O-].[Na+]>O>[C:3]([C:1](=[N:16][O:15][CH3:14])[CH2:6][N:7]1[C:11]([SH:12])=[N:10][N:9]=[N:8]1)([OH:5])=[O:4]参加物
5
実験手順
A solution of 1-oxalomethyl-1H-tetrazole-5-thiol (1.09 g) and methoxyamine hydrochloride (0.47 g) in water (15 ml) was adjusted to pH 6.5 with sodium bicarbonate and stirred at room temperature for 2 hours. After washing with ethyl acetate, the aqueous solution was adjusted to pH 1.8 with 10% hydrochloric acid, extracted with ethyl acetate, dried over magnesium sulfate and evaporated to give 1-(2-carboxy-2-methoxyiminoethyl)-1H-tetrazole-5-thiol (1.05 g), mp 84° to 86° C.
後処理
- washAfter washing with ethyl acetate
- extractionextracted with ethyl acetate
- dry with materialdried over magnesium sulfate
- customevaporated
出典と根拠
- ORDレコード
- ord-e30e4ed578b94f81970a418fa35f5ef0
- 出典データセット
- uspto-grants-1986_04
- 特許番号
- US04582908
反応ノート
読み込み中…