4,5-Diaminopyrimidine → 2-(2'-Methoxy-4'-chlorosulfonyl-phenyl)-purine hydrochloride

HRID 1380720

反応式

HRID 1380720 の反応式
[CH3:1][O:2][C:3]1[CH:11]=[C:10]([S:12]([Cl:15])(=[O:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5](O)=O.[NH2:16][C:17]1[C:22]([NH2:23])=[CH:21][N:20]=[CH:19][N:18]=1>>[ClH:15].[CH3:1][O:2][C:3]1[CH:11]=[C:10]([S:12]([Cl:15])(=[O:14])=[O:13])[CH:9]=[CH:8][C:4]=1[C:5]1[N:16]=[C:17]2[C:22]([NH:23][CH:19]=[N:18]2)=[CH:21][N:20]=1

参加物

3

反応物 2

HCID 837034,5-DiaminopyrimidineHCID 201845804-(Chlorosulfonyl)-2-methoxybenzoic acid

生成物 1

HCID 201845292-(2'-Methoxy-4'-chlorosulfonyl-phenyl)-purine hydrochloride

実験手順

Prepared analogously to Example C from 2.5 gm of 2-methoxy-4-chlorosulfonyl benzoic acid and 2.4 gm of 4,5-diamino-pyrimidine (crystalline product obtained from dihydorchloride and 1 mol of common salt) by refluxing for eight hours. The solid crude product was processed further without any purification.

後処理

  1. temperatureby refluxing for eight hours
  2. customThe solid crude product was processed further without any purification

出典と根拠

ORDレコード
ord-6d842c7706d44ef9bc1746be111d8ca0
出典データセット
uspto-grants-1986_04
特許番号
US04582837

関連ノート

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