Acetic Acid → HCID 13520695、化合物

反応式

CO[C:3]1[C:4]([CH2:14][C:15]#[N:16])=[C:5]([CH2:11][C:12]#[N:13])[CH:6]=[CH:7][C:8]=1[O:9][CH3:10].[BrH:17].[C:18]([OH:21])(=O)C>>[BrH:17].[CH3:18][O:21][C:7]1[C:8]([O:9][CH3:10])=[CH:3][C:4]2[CH2:14][C:15]([NH2:16])=[N:13][C:12]([Br:17])=[CH:11][C:5]=2[CH:6]=1

参加物

反応物 3

HCID 176Acetic Acid2 回

HCID 260Hydrogen Bromide

HCID 100362453,4-Dimethoxy-o-phenylenediacetonitrile

生成物 1

HCID 13520695HCID 13520695、化合物

実験手順

First 3,4-dimethoxy-o-phenylene-diacetonitrile (3.7 g, 0.017 mol) is suspended in glacial acetic acid (10 ml) and 30% hydrobromic acid in glacial acetic acid (12 ml) is added at 20° C. Then, the mixture is stirred for 3 hours at ambient temperature. The precipitate obtained is suction filtered, washed with glacial acetic acid and then with acetone/ether and dried. Yield: 5.3 g. Mp: 210°-211° C. (Decomp.)