1-(Triphenylphosphoranylidene)acetone → HCID 23035652、化合物

HRID 1381631ノート

反応式

HRID 1381631 の反応式
[C:1]([CH:4]=P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)(=[O:3])[CH3:2].[C:24]1([N:30]2[CH:33]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)[C:32](=O)[C:31]2=[O:41])[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1>C1C=CC=CC=1>[O:3]=[C:1]([CH3:4])/[CH:2]=[C:32]1/[C:31](=[O:41])[N:30]([C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=2)[CH:33]/1[C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1

参加物

4

反応物 2

HCID 150381-(Triphenylphosphoranylidene)acetoneHCID 133600861,4-Diphenylazetidine-2,3-dione

生成物 1

HCID 23035652HCID 23035652、化合物

試薬・触媒・溶媒 1

HCID 241Benzene溶媒2 回

実験手順

To a solution of 0.67 g of acetylmethylene triphenylphosphorane in 70 ml of benzene was added at room temperature under a nitrogen atmosphere a solution of 0.50 g of 1,4-diphenyl-2,3-azetidinedione in 30 ml of benzene, and the mixture was stirred overnight. After completion of the reaction, the benzene was evaporated, and the residue was applied to silica gel column chromatography (eluent; methylene chloride). The desired fractions were combined, the solvent was evaporated, and the residue was recrystallized from ethanol to give the title compound as pale yellow needles. Yield 0.32 g, m.p. 157.5°-158.5° C.

後処理

  1. customAfter completion of the reaction
  2. customthe benzene was evaporated
  3. customthe solvent was evaporated
  4. customthe residue was recrystallized from ethanol

出典と根拠

ORDレコード
ord-49b56e971ba74661bab039432acaa0e9
出典データセット
uspto-grants-1989_02
特許番号
US04803266

反応ノート

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