Methanethiol → 2-Methylthio-2,4-dimethylpentan-3-one
反応式
CO.[Na].[CH3:4][SH:5].Br[C:7]([CH3:14])([C:9](=[O:13])[CH:10]([CH3:12])[CH3:11])[CH3:8]>O>[CH3:4][S:5][C:7]([CH3:14])([C:9](=[O:13])[CH:10]([CH3:12])[CH3:11])[CH3:8]参加物
6
実験手順
A solution of 200 ml. of methanol containing 9.2 g. (0.40 mole) sodium metal was cooled in an ice-bath and saturated with gaseous methyl mercaptan. To this was added 77.2 g. (0.40 mole) of 2-bromo-2,4-dimethyl-pentan-3-one at room temperature and the resulting mixture stirred for two hours. The reaction mixture was diluted with water, extracted with ethyl ether, the extracts washed with water, brine and dried over anhydrous sodium sulfate. The ether was evaporated and the residue distilled in vacuo to afford 50.4 g. of product, B.P. 76° (20 mm.).
後処理
- additionTo this was added 77.2 g
- extractionextracted with ethyl ether
- washthe extracts washed with water, brine
- dry with materialdried over anhydrous sodium sulfate
- customThe ether was evaporated
- distillationthe residue distilled in vacuo
- customto afford 50.4 g
出典と根拠
- ORDレコード
- ord-b539443b8f764c2990f639993039dee7
- 出典データセット
- uspto-grants-1989_02
- 特許番号
- US04804782
反応ノート
読み込み中…