Methyl iodide → N-[6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-1-isobutyl-3-methyl-2-oxo-1,2-dihydro-1,8-naphthyridin-4-yl]-N-methylacetamide
反応式
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]3[C:15](=[N:16][C:17]=2[C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=2[Cl:25])[N:14]([CH2:26][CH:27]([CH3:29])[CH3:28])[C:13](=[O:30])[C:12]([CH3:31])=[C:11]3[NH:32][C:33](=[O:35])[CH3:34])=[CH:4][CH:3]=1.I[CH3:37]>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[C:10]3[C:15](=[N:16][C:17]=2[C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=2[Cl:25])[N:14]([CH2:26][CH:27]([CH3:28])[CH3:29])[C:13](=[O:30])[C:12]([CH3:31])=[C:11]3[N:32]([CH3:37])[C:33](=[O:35])[CH3:34])=[CH:4][CH:3]=1参加物
3
実験手順
Using the general procedure of EXAMPLE 12 the product of EXAMPLE 43 was reacted with iodomethane to afford the title compound. HPLC/MS: 542.2 (M+1), 544.2 (M+3); Rt=4.40 min.
出典と根拠
- ORDレコード
- ord-a59829e84d4e43d7ab8ea49062aa77ef
- 出典データセット