2-Amino-2-methyl-1-propanol → 2-((3-Fluoranthenylmethyl)-amino)-2-methyl-1-propanol hydrochloride
反応式
[ClH:1].[CH:2]1[C:16]2=[C:17]3[C:9]([C:10]4[C:15]2=[CH:14][CH:13]=[CH:12][CH:11]=4)=[CH:8][CH:7]=[CH:6][C:5]3=[C:4]([CH2:18][NH:19][C:20]([CH3:25])([CH2:23]O)[CH2:21][OH:22])[CH:3]=1.C1C2=C3C(C4C2=CC=CC=4)=CC=CC3=C(C=O)C=1.CC(N)(C)CO>CO.CCOCC>[ClH:1].[CH:2]1[C:16]2=[C:17]3[C:9]([C:10]4[C:15]2=[CH:14][CH:13]=[CH:12][CH:11]=4)=[CH:8][CH:7]=[CH:6][C:5]3=[C:4]([CH2:18][NH:19][C:20]([CH3:25])([CH3:23])[CH2:21][OH:22])[CH:3]=1参加物
5
実験手順
Using the reductive amination procedure outlines in 1D, 3-fluoranthenecarbaldehyde (1A) and 2-methyl-2-aminopropanol (Aldrich) gave 2-((3-fluoranthenylmethyl)-amino)-2-methyl-1-propanol hydrochloride, mp 288°-290° (dec), (CH3OH/Et2O), (C,H,Cl,N).