9-Bromononanal → HCID 86757099、化合物

HRID 1383286ノート

反応式

HRID 1383286 の反応式
[Br-].[C:2]([CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)([OH:4])=[O:3].[Br:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH:39]=O>O1CCCC1>[Br:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]/[CH:39]=[CH:10]\[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5][C:2]([OH:4])=[O:3]

参加物

4

反応物 2

HCID 5433309-BromononanalHCID 11027094(6-Carboxyhexyl)triphenylphosphonium bromide

生成物 1

HCID 86757099HCID 86757099、化合物収率 78%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

94 g (0.2 mol) of (6-carboxyhexyl)triphenylphosphonium bromide were suspended in 500 ml of tetrahydrofuran. 47 g (0.42 mol) of potassium t-butylate in 200 ml of tetrahydrofuran were added, followed by 50 g (0.22 mol) of 9-bromononanal. After work up and chromatography 52 g (78%) of 7Z-16-bromohexadec-7-enoic acid were obtained having the following characteristics: Z/E=90/10;

出典と根拠

ORDレコード
ord-714d7c830ef147c1a2d53a1c3f646100
出典データセット
uspto-grants-2001_07
特許番号
US06255276B1

反応ノート

読み込み中…