10-bromodecanal → HCID 88227136、化合物

HRID 1383289ノート

反応式

HRID 1383289 の反応式
[Br-].[C:2]([CH2:5][CH:6]([CH3:28])[CH2:7][CH2:8][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)([OH:4])=[O:3].[Br:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][CH2:37][CH2:38][CH:39]=O>C1COCC1>[CH3:28][CH:6]([CH2:7]/[CH:8]=[CH:39]\[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34][CH2:33][CH2:32][CH2:31][CH2:30][Br:29])[CH2:5][C:2]([OH:4])=[O:3]

参加物

4

反応物 2

HCID 1093343910-bromodecanalHCID 18348366HCID 18348366、化合物

生成物 1

HCID 88227136HCID 88227136、化合物収率 58.4%

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒2 回

実験手順

68.1 g (149 mmol) of (4-carboxy-3-methyl-butyl)-triphenylphosphonium bromide were placed in 150 ml of THF and treated with 33.4 g (298 mmol) of potassium t-butylate in 50 ml of THF. 35 g (149 mmol) of 10-bromodecanal were added to this mixture After usual work up 111.8 g of crude product were obtained and, after chromatography, 29 g of 3-methyl-5Z-15-bromopentadec-5-enoic acid were obtained having the following characteristics:

後処理

  1. customwere obtained

出典と根拠

ORDレコード
ord-9cb257bc81aa43f6858849b0bbdcf4ce
出典データセット
uspto-grants-2001_07
特許番号
US06255276B1

反応ノート

読み込み中…