Oxalyl chloride → 3-Cyclopentylthio-4-methoxybenzoyl chloride

HRID 1383525ノート

反応式

HRID 1383525 の反応式
[CH:1]1([S:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][C:15]=2[O:16][CH3:17])[C:10](O)=[O:11])[CH2:5][CH2:4][CH2:3][CH2:2]1.C(Cl)(=O)C([Cl:21])=O>ClCCl>[CH:1]1([S:6][C:7]2[CH:8]=[C:9]([CH:13]=[CH:14][C:15]=2[O:16][CH3:17])[C:10]([Cl:21])=[O:11])[CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

4

反応物 2

HCID 65578Oxalyl chlorideHCID 211878613-(Cyclopentylthio)-4-methoxybenzoic acid

生成物 1

HCID 211879163-Cyclopentylthio-4-methoxybenzoyl chloride

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

実験手順

A solution of 3-cyclopentylthio-4-methoxybenzoic acid (9 g; that is prepared as described in Reference Example 46) in dry dichloromethane (90 mL) under nitrogen is treated with oxalyl chloride (6.2 mL). After stirring at room temperature for 2 hours, the mixture is evaporated and dried under high vacuum, to give 3-cyclopentylthio-4-methoxybenzoyl chloride.

後処理

  1. customthat is prepared
  2. customthe mixture is evaporated
  3. customdried under high vacuum

出典と根拠

ORDレコード
ord-9be3b768741a4305bd2a6f61a08fcbb0
出典データセット
uspto-grants-2001_07
特許番号
US06255326B1

反応ノート

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