Hydrogen Bromide → [2-(2-Thienyl)ethylamino](2-chlorophenyl)acetamide hydrobromide
反応式
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][NH:8][CH:9]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Cl:19])[C:10]([NH2:12])=[O:11].[BrH:20]>CC(C)=O>[BrH:20].[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][CH2:7][NH:8][CH:9]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[Cl:19])[C:10]([NH2:12])=[O:11]参加物
4
実験手順
14.7 g (0.05 mol) of [2-(2-thienyl)ethylamino](2-chlorophenyl)acetamide, prepared as described in Example 7, is dissolve din 150 ml of acetone. To the solution 4 ml of 60% aqueous hydrogen bromide solution is added and the precipitated white crystals are filtered off, washed with acetone and dried.
後処理
- dissolutionis dissolve
- filtrationthe precipitated white crystals are filtered off
- washwashed with acetone
- customdried
出典と根拠
- ORDレコード
- ord-3aa938a98c254de18ce0bedfd69008d4
- 出典データセット
- uspto-grants-2001_07
- 特許番号
- US06258961B1
反応ノート
読み込み中…