Iodine → HCID 21706514、化合物

HRID 1387278

反応式

HRID 1387278 の反応式
[CH3:1][C:2]1[CH:7]=[CH:6][NH:5][C:4](=[O:8])[C:3]=1[N+:9]([O-:11])=[O:10].II.[I:14]([O-])(=O)=O.[Na+].O>C(O)(=O)C.S(=O)(=O)(O)O>[I:14][C:7]1[C:2]([CH3:1])=[C:3]([N+:9]([O-:11])=[O:10])[C:4](=[O:8])[NH:5][CH:6]=1

参加物

7

反応物 4

HCID 807IodineHCID 962WaterHCID 3453702-Hydroxy-4-methyl-3-nitropyridineHCID 23675764Sodium Iodate

生成物 1

HCID 21706514HCID 21706514、化合物

試薬・触媒・溶媒 2

HCID 176Acetic Acid溶媒HCID 1118Sulfuric Acid溶媒

反応条件

温度
75 °C

実験手順

To a solution of 4-methyl-3-nitro-2-pyridone (2.00 g, 13 mmol) in acetic acid (12 mL) and concentrated sulfuric acid (1.6 ml,) was added iodine (1.32 g) and sodium iodate (0.55 g). The mixture was heated at 75° C. for 2.5 hours and then stirred at rt overnight. Water (100 mL) was added, and the precipitated 5-iodo-4-methyl-3-nitro-2-pyridone was collected by filtration (2.97 g, 82%).

後処理

  1. filtrationthe precipitated 5-iodo-4-methyl-3-nitro-2-pyridone was collected by filtration (2.97 g, 82%)

出典と根拠

ORDレコード
ord-4e8af721267749e8b617049bd221cc3a
出典データセット
uspto-grants-2001_07
特許番号
US06268365B1

関連ノート

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