Pentachlorophenol → HCID 131710245、化合物

HRID 1388091

反応式

HRID 1388091 の反応式
[CH3:1][O:2][C@H:3]1[O:8][C@H:7]([CH2:9][OH:10])[C@@H:6]([OH:11])[C@H:5]([OH:12])[C@H:4]1[OH:13].[Cl:14][C:15]1[C:20]([OH:21])=[C:19]([Cl:22])[C:18]([Cl:23])=[C:17]([Cl:24])[C:16]=1[Cl:25].[Al].[CH2:27]([O:29][P:30]([O:34][CH2:35][CH3:36])[O:31][CH2:32][CH3:33])[CH3:28].[CH2:37]1[O:40][CH:38]1[CH3:39]>[Fe].C(N(CC)CC)C>[CH3:1][O:2][C@H:3]1[O:8][C@H:7]([CH2:9][OH:10])[C@@H:6]([OH:11])[C@H:5]([OH:12])[C@H:4]1[OH:13].[CH2:27]([O:29][P:30]([O:34][CH2:35][CH3:36])[O:31][CH2:32][CH3:33])[CH3:28].[Cl:14][C:15]1[C:20]([OH:21])=[C:19]([Cl:22])[C:18]([Cl:23])=[C:17]([Cl:24])[C:16]=1[Cl:25].[CH2:37]1[O:40][CH:38]1[CH3:39]

参加物

8

反応物 5

HCID 992PentachlorophenolHCID 6378Propylene Oxide2 回HCID 31215Triethyl phosphiteHCID 64947methyl alpha-D-glucopyranosideHCID 5359268Aluminum

生成物 1

HCID 131710245HCID 131710245、化合物

試薬・触媒・溶媒 2

HCID 23925Iron触媒HCID 8471Triethylamine溶媒

反応条件

温度
122 °C

実験手順

A 5-liter flask, standardly equipped, was charged with 776 grams of alpha-methylglucoside, 1264 grams of pentachlorophenol containing about 750 ppm of aluminum and iron compounds, 240 grams of triethylphosphite, and heated to 122° C. 1025 ml. of propylene oxide was added at 122°-138° C. over a 6-hour period. Then 48 grams of triethylamine was added, followed by 265 ml. more of propylene oxide to reduce the acid number to less than 1. The mixture was then stripped for 2 hours at 80°-85° C./2 mm. Hg to remove volatiles. The oxypropylated product weighed 3827 grams and analyzed as follows:

後処理

  1. customA 5-liter flask, standardly equipped
  2. custom/2 mm. Hg to remove volatiles

出典と根拠

ORDレコード
ord-c29daa84ee204d9e90e5722daaf3d95c
出典データセット
uspto-grants-1984_02
特許番号
US04430247

関連ノート

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