Allyl bromide → N,N-Dimethyl-N-(prop-2-en-1-yl)octadecan-1-aminium chloride

HRID 1388870ノート

反応式

HRID 1388870 の反応式
[CH3:1][N:2]([CH3:21])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20].[CH2:22]([Cl:25])[CH:23]=[CH2:24].C(Br)C=C.C(=O)(O)[O-].[Na+]>C(O)(C)C>[Cl-:25].[CH2:22]([N+:2]([CH3:1])([CH3:21])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[CH:23]=[CH2:24]

参加物

6

反応物 4

HCID 7841Allyl bromideHCID 7850Allyl chlorideHCID 15365DimethyloctadecylamineHCID 516892Sodium Bicarbonate

生成物 1

HCID 20468836N,N-Dimethyl-N-(prop-2-en-1-yl)octadecan-1-aminium chloride

試薬・触媒・溶媒 1

HCID 3776Isopropanol溶媒

実験手順

A 2-liter reaction vessel equipped with a mechanical stirrer and a reflux condenser was charged with 660.0 gm. dimethyl octadecyl amine, 199.0 gm. (2.19 mol) allyl chloride, 13.3 (0.11 mol) gm. allyl bromide, 20 gm. sodium bicarbonate, and 350 ml. isopropyl alcohol. This mixture was heated under reflux overnight. Analyses of a filtered aliquot indicated the reaction was complete. The mixture was filtered and upon analysis had an Effective gram MW of 496.74.

後処理

  1. customA 2-liter reaction vessel
  2. customequipped with a mechanical stirrer and a reflux condenser
  3. additionwas charged with 660.0 gm
  4. temperatureThis mixture was heated
  5. temperatureunder reflux overnight
  6. filtrationThe mixture was filtered and upon analysis

出典と根拠

ORDレコード
ord-31c201d1fc7b4a01b6dd2e904ca8cfbe
出典データセット
uspto-grants-1984_02
特許番号
US04434076

反応ノート

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