Hydrochloric Acid → HCID 20298226、化合物
反応式
C([O:3][C:4](=[O:16])[C:5]([C:7]1[NH:8][C:9]([S:12][CH2:13][CH2:14][CH3:15])=[CH:10][CH:11]=1)=[O:6])C.[OH-].[Na+].Cl>O>[CH2:13]([S:12][C:9]1[NH:8][C:7]([C:5](=[O:6])[C:4]([OH:16])=[O:3])=[CH:11][CH:10]=1)[CH2:14][CH3:15]参加物
5
実験手順
A mixture of 5-n-propylthio-2-pyrrolylglyoxylic acid ethyl ester (2.4 g.) and sodium hydroxide (1.0 g.) in water (100 ml.) was heated on a steam bath for 3 hours. The solution was cooled, acidified to pH 1 with dilute hydrochloric acid and the product extracted with chloroform. Evaporation of the solvent and recrystallization from petroleum ether (B.P. 40°-60°) gave 5-n-propylthio-2-pyrrolylglyoxylic acid (0.7 g.) as yellow crystals, M.P. 87°. Found: C, 50.34; H, 5.21; N, 6.54. C9H11NO3S requires: C, 50.68; H, 5.20; N, 6.57%.
後処理
- temperaturewas heated on a steam bath for 3 hours
- temperatureThe solution was cooled
- extractionthe product extracted with chloroform
- customEvaporation of the solvent and recrystallization from petroleum ether (B.P. 40°-60°)
出典と根拠
- ORDレコード
- ord-3697d3a522074b2d803f8b098d3e5694
- 出典データセット
- uspto-grants-1981_01
- 特許番号
- US04243672
反応ノート
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