Acetone → HCID 88766983、化合物

HRID 1389961

反応式

HRID 1389961 の反応式
[C:1]([CH2:3][CH2:4][PH:5](=[O:10])[CH2:6][CH2:7][C:8]#[N:9])#[N:2].[CH3:11][C:12]([CH3:14])=[O:13].CN(C)C(=NC)N(C)C>C(N(CC)CC)C>[CH3:11][C:12]([P:5](=[O:10])([CH2:6][CH2:7][C:8]#[N:9])[CH2:4][CH2:3][C:1]#[N:2])([OH:13])[CH3:14]

参加物

5

反応物 3

HCID 180AcetoneHCID 139457N,N,N',N',N''-PentamethylguanidineHCID 178511210HCID 178511210、化合物

生成物 1

HCID 88766983HCID 88766983、化合物収率 88%

試薬・触媒・溶媒 1

HCID 8471Triethylamine溶媒

実験手順

To a mixture of 0.1 mol of bis(2-cyanoethyl)phosphine oxide and 0.1 mol of acetone was added 1.0 gram of either triethyl amine or pentamethyl guanidine. The mixture was heated for 2 hours at steam bath temperatures. The resulting solid was filtered and recrystallized from acetone to give an 88% yield of product, m.p. 124°-125° C.

後処理

  1. temperatureThe mixture was heated for 2 hours at steam bath temperatures
  2. filtrationThe resulting solid was filtered
  3. customrecrystallized from acetone

出典と根拠

ORDレコード
ord-842a394f7c5a4c3cb602647f6bf0e708
出典データセット
uspto-grants-1981_01
特許番号
US04247447

関連ノート

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