Acetone → 1,1-Dimethylhydroxymethylbis(2-cyanoethyl)-phosphine oxide
反応式
[C:1]([CH2:3][CH2:4][PH:5](=[O:10])[CH2:6][CH2:7][C:8]#[N:9])#[N:2].[CH3:11][C:12]([CH3:14])=[O:13].CN(C)C(=NC)N(C)C>C(N(CC)CC)C>[CH3:11][C:12]([P:5](=[O:10])([CH2:6][CH2:7][C:8]#[N:9])[CH2:4][CH2:3][C:1]#[N:2])([OH:13])[CH3:14]参加物
5
実験手順
To a mixture of 0.1 mol of bis(2-cyanoethyl)phosphine oxide and 0.1 mol of acetone was added 1.0 gram of either triethyl amine or pentamethyl guanidine. The mixture was heated for 2 hours at steam bath temperatures. The resulting solid was filtered and recrystallized from acetone to give an 88% yield of product, m.p. 124°-125° C.
後処理
- temperatureThe mixture was heated for 2 hours at steam bath temperatures
- filtrationThe resulting solid was filtered
- customrecrystallized from acetone
出典と根拠
- ORDレコード
- ord-842a394f7c5a4c3cb602647f6bf0e708
- 出典データセット
- uspto-grants-1981_01
- 特許番号
- US04247447
反応ノート
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