Potassium Carbonate → 3-(Benzyloxy)piperidine

HRID 1390496ノート

反応式

HRID 1390496 の反応式
C([N:4]1[CH2:9][CH2:8][CH2:7][CH:6]([O:10][CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:5]1)(=O)C.[OH-].[Na+].C(=O)([O-])[O-].[K+].[K+]>O>[CH2:11]([O:10][CH:6]1[CH2:7][CH2:8][CH2:9][NH:4][CH2:5]1)[C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1

参加物

5

反応物 3

HCID 11430Potassium CarbonateHCID 14798Sodium HydroxideHCID 205061191-Acetyl-3-benzyloxypiperidine

生成物 1

HCID 199606043-(Benzyloxy)piperidine

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

1-Acetyl-3-benzyloxypiperidine (0.043 mole), sodium hydroxide (0.086 mole) and water (30 ml.) are combined and refluxed for 24 hours. The reaction mixture is saturated with potassium carbonate and extracted three times with ether. The ether is removed by evaporation and the yellow oil is distilled at 92°-94° C. (0.3 mm Hg.).

後処理

  1. temperaturerefluxed for 24 hours
  2. extractionextracted three times with ether
  3. customThe ether is removed by evaporation
  4. distillationthe yellow oil is distilled at 92°-94° C. (0.3 mm Hg.)

出典と根拠

ORDレコード
ord-b342f3901ed145b683d69f49a2bf3e13
出典データセット
uspto-grants-1979_02
特許番号
US04138399

反応ノート

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