1-Butanol → HCID 20332638、化合物

HRID 1390598ノート

反応式

HRID 1390598 の反応式
[Br:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:6]=1[Cl:12])=[O:4].[Br:13][C:14]1[CH:19]=[CH:18][C:17]([S:20][CH2:21][CH:22]([OH:25])[CH2:23]O)=[CH:16][CH:15]=1.CC1C=CC(S(O)(=O)=O)=CC=1.C(O)CCC>O.C1C=CC=CC=1>[Br:1][CH2:2][C:3]1([C:5]2[CH:10]=[CH:9][C:8]([Cl:11])=[CH:7][C:6]=2[Cl:12])[O:25][CH:22]([CH2:21][S:20][C:17]2[CH:18]=[CH:19][C:14]([Br:13])=[CH:15][CH:16]=2)[CH2:23][O:4]1

参加物

7

反応物 4

HCID 2631-ButanolHCID 6101p-Toluenesulfonic acidHCID 758282-Bromo-1-(2,4-dichlorophenyl)ethan-1-oneHCID 203326623-[(4-Bromophenyl)sulfanyl]propane-1,2-diol

生成物 1

HCID 20332638HCID 20332638、化合物

試薬・触媒・溶媒 2

HCID 241Benzene溶媒HCID 962Water溶媒

実験手順

A mixture of 13.6 parts of 2-bromo-1-(2,4-dichlorophenyl)-1-ethanone, 15.8 parts of 3-(4-bromophenylthio)-1,2-propanediol, 3 parts of 4-methylbenzenesulfonic acid, 180 parts of butanol and 90 parts of benzene is stirred and refluxed for 12 hours with water-separator. The reaction mixture is evaporated and the residue is dissolved in trichloromethane. The solution is stirred with silica gel for 30 minutes. The latter is filtered off and the filtrate is evaporated, yielding A + B 2-(bromomethyl)-4-(4-bromophenylthiomethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane as a residue.

後処理

  1. customThe reaction mixture is evaporated
  2. dissolutionthe residue is dissolved in trichloromethane
  3. stirringThe solution is stirred with silica gel for 30 minutes
  4. filtrationThe latter is filtered off
  5. customthe filtrate is evaporated

出典と根拠

ORDレコード
ord-ffc44ca544264f718196f037fa26ec9c
出典データセット
uspto-grants-1979_02
特許番号
US04139540

反応ノート

読み込み中…