Tetrahydrofuran → 1-{6-Benzyloxy-1-[4-(2-pyrrolidin-1-yl-ethoxy)phenyl]-3,4-dihydro-1H-isoquinolin-2-yl}-2,2-dimethylpropan-1-one

反応式

[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[c:16]([cH:17][cH:18]1)[CH:15]([c:19]1[cH:20][cH:21][c:22]([O:25][CH2:26][CH2:27][N:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)[cH:23][cH:24]1)[NH:14][CH2:13][CH2:12]2.[CH2:47]1[O:48][CH2:49][CH2:50][CH2:51]1.[CH3:33][CH2:34][N:35]([CH2:36][CH3:37])[CH2:38][CH3:39].[CH3:40][C:41]([C:42](=[O:43])[Cl:44])([CH3:45])[CH3:46]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]2[c:16]([cH:17][cH:18]1)[CH:15]([c:19]1[cH:20][cH:21][c:22]([O:25][CH2:26][CH2:27][N:28]3[CH2:29][CH2:30][CH2:31][CH2:32]3)[cH:23][cH:24]1)[N:14]([C:42]([C:41]([CH3:40])([CH3:45])[CH3:46])=[O:43])[CH2:13][CH2:12]2