Hydroxyamine hydrochloride → HCID 136227082、化合物

反応式

[CH2:1]([C:3]1[CH:17]=[CH:16][C:6]([C:7]([C:9]2[CH:14]=[CH:13][C:12]([F:15])=[CH:11][CH:10]=2)=O)=[C:5]([OH:18])[CH:4]=1)[CH3:2].Cl.[NH2:20][OH:21]>>[CH2:1]([C:3]1[CH:17]=[CH:16][C:6]([C:7](=[N:20][OH:21])[C:9]2[CH:14]=[CH:13][C:12]([F:15])=[CH:11][CH:10]=2)=[C:5]([OH:18])[CH:4]=1)[CH3:2]

参加物

反応物 2

HCID 443297Hydroxyamine hydrochloride

HCID 12562657(4-Ethyl-2-hydroxyphenyl)(4-fluorophenyl)methanone

生成物 1

HCID 136227082HCID 136227082、化合物

実験手順

4-Ethyl-4'-fluoro-2-hydroxybenzophenone (21.0 g, 80% pure) was treated with hydroxylamine hydrochloride (24.0 g) in a manner similar to that in Example 3, to give, after recrystallisation from benzene, the title compound as a white crystalline solid (10.7 g), m.p. 130°-2° C.

後処理

customto give
customafter recrystallisation from benzene

出典と根拠

ORDレコード: ord-f5798c2b2b0444e2b3b9151ea5c8cfa6
出典データセット: uspto-grants-1979_02
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04141995

反応ノート

読み込み中…

参加物