Acetophenone → (1-Phenylethylidene)hydrazine

HRID 1391409ノート

反応式

HRID 1391409 の反応式
[C:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)(=O)[CH3:2].[NH2:10][NH2:11]>C(O)C>[C:1](=[N:10][NH2:11])([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1)[CH3:2]

参加物

4

反応物 2

HCID 7410AcetophenoneHCID 9321Hydrazine

生成物 1

HCID 114650(1-Phenylethylidene)hydrazine収率 69%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

acetophenone (2.0 g, 16 mmol) is diluted in 16 ml of absolute ethanol and then hydrazine (2.3 ml, 48 mmol) is added. The mixture is heated to reflux temperature. After 2 h, the solvent is evaporated and the residue is taken up in ether (150 ml). The medium is washed with water (100 ml). After drying over Na2SO4, the ether is evaporated off. A pale yellow oil (1.5 g, 11 mmol, 69%) is obtained.

後処理

  1. temperatureThe mixture is heated
  2. temperatureto reflux temperature
  3. customthe solvent is evaporated
  4. washThe medium is washed with water (100 ml)
  5. dry with materialAfter drying over Na2SO4
  6. customthe ether is evaporated off

出典と根拠

ORDレコード
ord-64bcc0fe4cae47a4881895edeae687f4
出典データセット
uspto-grants-2008_03
特許番号
US07338805B2

反応ノート

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